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Atrial or ventricular fibrillation, ventricular tachycardia, QT interval prolongation, Torsades de Pointes, myocardial clozaril infarction, cardiac arrest, and periorbital edema .
It may be necessary to reduce the CLOZARIL dose in patients with significant clozaril and agranulocytosis clozaril contraindications clozaril generic adverse effects of clozaril renal or hepatic impairment, or in CYP2D6 poor metabolizers [see Use in Specific Populations] .
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See Tables 2 or 3 for appropriate ANC monitoring based on the level of neutropenia if abrupt treatment discontinuation is necessary because clozaril of moderate to severe neutropenia .

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