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-Exogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activity; prednisolone acetate vs prednisone prednisolone acetate dosage for iritis prednisolone side effects consider time of maximal adrenal cortex activity (2 AM to 8 AM) when dosing .
Kaposi’s sarcoma has been reported among patients prednisolone receiving corticosteroid therapy; discontinuation may result in clinical remission .
Uses: As an anti-inflammatory or immunosuppressive agent when corticosteroid therapy is appropriate, such as treatment of certain allergic states; nervous system, neoplastic, or renal conditions; endocrine, rheumatologic, or hematologic disorders; collagen, dermatologic, prednisolone ophthalmic, respiratory, or gastrointestinal diseases; specific infectious diseases or conditions related to organ transplantation .

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